Thiamine Deficiency Disease, Dysautonomia, and High Calorie Malnutrition
Thiamine Deficiency Disease, Dysautonomia, and High-Calorie Malnutrition dive into thiamine deficiency and its effects on the brainstem's functions as well as the autonomic nervous system through metabolic alterations in mitochondrial levels.
Thiamine deficiency has the power to disrupt mitochondrial oxidative metabolism, eventually leading to beriberi. As one of the earliest forms of dysautonomia, beriberi is often viewed as a prototypical example of this group of disorders.
Beriberi results in a wide variety of symptoms, such as autonomic nervous system dysfunctions, motor nerve, and muscle paralysis, decreased body coordination and balance, encephalopathy, and edema.
With the increasing number of cases of thiamine deficiency in western countries due to excessive consumption of refined carbohydrates or alcohol abuse, Dysautonomia and High-Calorie Malnutrition offers an in-depth discussion on the mechanisms behind thiamine's deficiency and its effects on many of the major organ systems.
This book also explores how high-calorie malnutrition is linked to dysautonomia and neurodegenerative diseases. This book provides a comprehensive overview of neurological, radiological, and biochemical markers used to diagnose thiamine deficiency and the mechanisms behind the disease.
Additionally, this book provides comprehensive descriptions of potential interventions to treat the effects of thiamine deficiency, including vitamin supplementation, lifestyle modification, dietary changes, and cognitive behavior therapy.
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