Dr. David Sinclair, Ph.D.
A renowned authority on the genetics of aging and longevity, author, and host of Lifespan with Dr. David Sinclair podcast.
Dr. David A. Sinclair, AO, Ph.D., is a lecturer in the Department of Genetics at Harvard Medical School and co-director of the Paul F Dr. Paul F Glenn Center for Biology of Aging Research at Harvard Medical School.
Dr. David Sinclair is an expert on aging and its effects. He received his Ph.D. in Molecular Genetics from the University of New South Wales, Sydney in 1995 and has dedicated his career to understanding why we age and how we can slow down the process.
After working with Dr. Leonard Guarente at M.I.T., where they discovered a cause of yeast aging as well as the role played by Sir2 in epigenetic changes brought on by genome instability, he was recruited to Harvard Medical School in 1999. There, he has been teaching aging biology and translational medicine for 16 years now.
His main area of research is sirtuins, enzymes that change proteins in response to NAD+ level changes or caloric restriction (CR). He is also interested in chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, and cancer.
Dr. Sinclair is a co-founder of several biotechnology firms (Sirtris, Ovascience, Genocea, Cohbar, MetroBiotech, ArcBio) as well as a director of several more.
He also serves as co-editor and co-chief editor of the journal Aging. His research has been covered in five books and two documentary films.
Podcast hosted by Dr. David Sinclair, Ph.D.
Lifespan with Dr. David Sinclair
Dr. David Sinclair, a world-renowned aging research doctor, and Ph.D., hosts the Lifespan Podcast distinct from his teaching and research roles at Harvard Medical School. As a professor of genetics and co-director of Harvard Medical School's Center for Biology of Aging Research, Dr. Sinclair provides listeners with insights on cutting-edge...Learn more about Lifespan with Dr. David Sinclair
Book written by Dr. David Sinclair, Ph.D.
Lifespan
Why We Age - and Why We Don't Have To
Sep 10, 2019 | 432 PagesA groundbreaking book from a well-known Harvard Medical School scientist that has been deemed one of the Time's most influential people. Aging is a fact of life, it seems. But what if everything we've been told about aging up to this point is wrong? What if we had the power to decide how long we lived for? In this world-changing book, Dr....Learn more about Lifespan
Topics discussed by Dr. David Sinclair, Ph.D.
Topics discussed by Dr. David Sinclair, Ph.D. in books and podcast appearances.
Aging
Slow down the process...and age gracefully! Aging is inevitable. Everyone will face it sooner or later. There are, however, things that can be done to slow the aging process and keep one's body...
Longevity
I want to live forever! Longevity refers to the length of time a particular species can live and produce offspring. In humans, longevity is often measured by life...
Cells
We are made of cells! Cells are the basic building blocks of all living organisms. The human body is composed of trillions of cells that perform specific functions. There...
Fasting
What pattern of eating are you following? Fasting has been practiced throughout history for religious, spiritual, and health reasons. In recent years, fasting has become a popular weight loss...
Cold Therapy
Ice, ice, baby! Cold therapy, also known as cryotherapy, involves the use of cold temperatures to alleviate pain and inflammation. One type of cold therapy is the...
Mitochondria
Essential for the health and well-being of our cells! Mitochondria are organelles in the cells of most eukaryotic organisms. They range in size from 0.5 to 1.0 micrometers and are typically spherical or...
AMPK
A central regulator of energy homeostatis! AMPK is an enzyme that plays a vital role in metabolism. It is responsible for sensing the energy levels in cells and regulating them...
mTOR
Every barrier is meant to be broken... mTOR is a protein that is responsible for cell growth, proliferation, and survival. When mTOR is activated, it signals the cell to start making new...
DNA
Your DNA is the code that makes up your genetic information! DNA is a nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms and many viruses....